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Saccharomyces boulardii (S. Boulardii) is a strain of non-pathogenic yeast first discovered by Henry Boulard in 1920. Because S. Boulardii is a yeast microbe, it cannot be killed by antibiotics. 

There is a wealth of research data supporting the use of S. Boulardii in gastro intestinal conditions. The highest quality S. Boulardii preparations are lyophilized (freeze dried) and generally contain 5 billion CFU (colony forming units).